Primary cell cultures closely mimic natural cell behavior, offering high physiological relevance but with limited lifespan and complexity in maintenance. Immortalized cell lines, on the other hand, provide unlimited growth and reliability for high-throughput studies but may lack natural accuracy. Each serves distinct research needs, advancing our understanding of biology and medicine.

https://www.apsense.com/article/827018-understanding-primary-cell-cultures-and-immortalized-cell-lines-in-research.html
 

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